Original Viagra (Pfizer) 100mg

The Story of Viagra's Discovery — A Laboratory Accident That Changed Medicine

Sildenafil was not designed to treat erectile dysfunction. In 1989, Pfizer researchers in Sandwich, UK synthesised compound UK-92480 in search of a treatment for angina pectoris and high blood pressure. The mechanism of action was promising — inhibiting PDE5 to relax vascular smooth muscle — but phase II clinical trials showed modest effects on angina.

What the researchers did observe was unexpected: male trial participants reported spontaneous erections and improved erectile function. Rather than dismissing this as a side effect, Pfizer redirected development towards erectile dysfunction. The patent was approved in 1996, and on 27 March 1998 the FDA approved Viagra — making it the first oral treatment for ED approved in the United States. The AEMPS authorised it in Spain the same year.

In its first weeks on the market, Viagra generated unprecedented demand in pharmaceutical history. In 2012 — its last full year under patent — Pfizer recorded over 2 billion dollars in Viagra sales alone.

Original Viagra vs Generic Viagra — Real Differences and the Price Myth

Pharmacological conclusion: Original Viagra and generic are therapeutically equivalent. The price difference is solely because Pfizer bore the research and development costs (estimated at over 700 million dollars). Those who choose the original do so primarily for certainty of authenticity and brand trust, not for greater efficacy.

Why Some People Choose the Original Despite the Price

• Certainty of authenticity: Pfizer packaging has verifiable security features (holograms, traceable batch code, embossed text on tablet). In a market where counterfeits circulate, the original eliminates that risk
• First experience: Some men prefer to start with the original to have a reliable reference before trying generics
• Excipient tolerance: In rare cases, differences in excipients (dyes, binders) between generics may produce differences in GI tolerability — not efficacy. The original has a well-known standard formulation
• Brand psychology: For some men, the confidence generated by the name «Pfizer» has real therapeutic value — the placebo effect added to the pharmacological effect can improve outcomes

How to Recognise an Authentic Pfizer Viagra

Dosage and How to Take

• Standard dose: 50mg taken 30–60 minutes before sexual activity
• Dose adjustment: If 50mg is insufficient, increase to 100mg. If it causes troublesome side effects, reduce to 25mg
• Maximum frequency: 1 tablet per 24 hours
• With meals: Take on an empty stomach or with a light meal. Fatty meals delay absorption by up to 60 additional minutes
• Alcohol: Maximum 1–2 drinks. Excess alcohol antagonises the vasodilatory effect
• Grapefruit: Avoid completely — inhibits CYP3A4 and may unpredictably raise sildenafil levels

Side Effects

Absolute Contraindications

• Nitrates (nitroglycerin, isosorbide dinitrate or mononitrate) — severe potentially fatal hypotension
• Poppers (amyl or butyl nitrite)
• Riociguat (Adempas)
• Heart attack or stroke in the last 3–6 months
• Unstable angina or severe heart failure
• Severe hypotension (<90/50 mmHg)
• History of NAION (non-arteritic anterior ischaemic optic neuropathy)
• Under 18 years of age | Women

Frequently Asked Questions

If the generic is equally effective, why buy the original? The pharmacological efficacy is identical. Choosing the original is based on certainty of authenticity, familiarity with the formulation and brand trust. For many men the generic is the most rational option. For those who prefer maximum assurance that they are taking exactly what they expect — the original makes sense.

Does Original Viagra have a better onset of action than generic? No. Both have the same onset of 30–60 minutes and the same duration of 4–6 hours. The active ingredient, dose and bioequivalence are the same.

Can I split a 100mg Original Viagra tablet to get 50mg? Yes — the tablet can be cut in half. Pfizer designed the diamond shape precisely to facilitate splitting. A tablet cutter ensures the most accurate division.

How do I know if the Viagra I have bought is genuine? Check the 5 elements described above: blue diamond shape, «Pfizer» / «VGR 100» embossing, hologram on the box, traceable batch number, Spanish-language leaflet with AEMPS number.

Related Products

• Generic Viagra — same efficacy, up to 75% more economical
• Kamagra 100mg — sildenafil Ajanta Pharma, GMP certified
• Kamagra Oral Jelly — sildenafil gel, onset in 15 min
• Viagra Soft Tabs — chewable tablets, faster absorption
• Original Cialis (Eli Lilly) — branded tadalafil, up to 36 hours

Delivery Across Spain

We ship in 4–7 days to all provinces in discreet neutral packaging: Barcelona — Madrid — Valencia — Alicante — Seville — Malaga — Zaragoza — Bilbao — Vigo — A Coruna — Murcia — Palma de Mallorca — Las Palmas — Santa Cruz de Tenerife — Valladolid — Cordoba — Granada — Oviedo — Pamplona — Santander — Vitoria — Elche — Badalona — Cartagena — Jerez de la Frontera — Sabadell — Mostoles — Alcala de Henares — and all other localities in Spain.

The information is for educational purposes only and does not replace medical advice. Before taking sildenafil, consult your doctor especially if you take nitrates, alpha-blockers or other cardiovascular medications.