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Trial Packs for Erectile Dysfunction — Why Urologists Recommend Trying All Three PDE5 Inhibitors

Trial Packs for Erectile Dysfunction — Why Urologists Recommend Trying All Three PDE5 Inhibitors

Medically reviewed by Dr. Carlos Mendez Ruiz, Specialist in Urology and Sexual Health, Colegio Oficial de Medicos de Alicante (Reg. No.: 03-45678) — Updated January 2026

Trial packs contain a sample of the three major PDE5 inhibitors — sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) — in a single purchase. Their purpose is practical: all three work by the same mechanism but have distinct pharmacological profiles, and individual response varies significantly between patients. Before committing to one medication long-term, it makes clinical sense to try each one. We offer two packs: generic and original brand.

Why Not All Men Respond the Same Way to the Three PDE5 Inhibitors

Key clinical fact: Approximately 30–40% of patients who do not respond to sildenafil do respond to tadalafil or vardenafil, and vice versa. The EAU (European Association of Urology) guidelines recommend switching PDE5 inhibitor before considering more invasive treatments. Individual response depends on vascular profile, age, comorbidity and genetic factors in drug metabolism.

Feature	Sildenafil Viagra / Kamagra	Tadalafil Cialis	Vardenafil Levitra
Onset of action	30–60 min	30–60 min	10–25 min
Duration of effect	4–6 hours	Up to 36 hours	4–6 hours
Influence of fatty meals	High — better on empty stomach	None	Mild
Efficacy in diabetics	63%	~65%	72%
Blue vision effect	Common (1–10%)	Very rare	Very rare
Approved daily therapy	Not approved	Yes — 2.5mg/5mg/day	Yes — 5mg/day
Best for	Classic first choice, maximum evidence	Spontaneity, frequent use, maximum duration	Speed, diabetics, no response to Viagra

Our Two Trial Packs

Generic Trial Pack

All three generics — same efficacy, best price

Generic Sildenafil (Viagra) 100mg

The world's most widely used PDE5. Onset 30–60 min. Clinically proven over 30+ years.

Generic Tadalafil (Cialis) 20mg

The only one with up to 36 hours duration. Food-independent. Ideal for spontaneity.

Generic Vardenafil (Levitra) 20mg

The fastest (10–25 min). Highest efficacy in diabetics (72%). Minimal visual disturbance.

Why choose generic

Same clinical efficacy as originals at up to 80% lower price. GMP-certified manufacturers. Bioequivalent per EMA regulation.

View Generic Trial Pack

Original Trial Pack

All three brand originals — Pfizer, Eli Lilly and Bayer

Original Viagra (Pfizer) 100mg

Pfizer's original blue Viagra. Diamond-shaped blue tablet embossed «PFIZER» and «VGR 100». Verifiable authenticity chain.

Original Cialis (Eli Lilly) 20mg

Eli Lilly's original yellow Cialis. Almond-shaped yellow tablet embossed «C20». The only one lasting up to 36 hours.

Original Levitra (Bayer) 20mg

Bayer's original orange Levitra. Round orange tablet embossed «BAYER» and «20». Highest efficacy in diabetics (72%).

Why choose original

Absolute authenticity certainty with the reference tablets from Pfizer, Eli Lilly and Bayer. For those who prioritise brand guarantee over price.

View Original Trial Pack

Generic Trial Pack

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Brand Trial Packs

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How to Use the Trial Packs — Recommended Protocol

Week 1 — Sildenafil

Take 30–60 min before
Preferably on empty stomach or light meal
Max 1–2 drinks alcohol
Note: onset time, duration, side effects, overall satisfaction

Week 2 — Tadalafil

Take 30–60 min before (or up to 36h before)
With or without food — irrelevant
Test the 12–24 hour window to assess duration
Note same parameters to compare

Week 3 — Vardenafil

Take 25–60 min before
Avoid very fatty meals
Especially evaluate onset speed vs sildenafil
Compare overall satisfaction with previous ones

After the 3 trials: The active ingredient with the best combination of efficacy, tolerability and convenience for your profile is the one to continue with. If none of the three delivers results, consult a urologist — it may indicate an underlying organic cause requiring assessment.

Frequently Asked Questions

Does it make sense to try all 3 if Viagra already works for me? It depends on what you're looking for. If sildenafil works well for you, there's no need to change. But if it produces bothersome side effects (blue vision, intense headache), or you want longer duration or more spontaneity, a trial pack lets you compare first-hand without committing to a full box of another product.

What is the difference between the Generic Trial Pack and the Original Pack? The active ingredient, dose and efficacy are identical. The difference is the manufacturer: the Generic Pack includes bioequivalent generic versions (up to 80% cheaper), the Original Pack includes brand-name drugs from Pfizer, Eli Lilly and Bayer with their identifiable tablets and guaranteed authenticity chain.

Can I take all three on the same day to compare? No — only one PDE5 inhibitor in 24 hours. Comparison must be done on separate occasions to properly evaluate each one.

If I don't respond well to one, will the others also fail? Not necessarily. As stated in the EAU clinical guidelines, 30–40% of patients who do not respond to sildenafil do respond to tadalafil or vardenafil. This is why trial packs have real clinical value — not just marketing.

Delivery Across Spain

We ship in 4–7 days to all provinces in discreet neutral packaging: Barcelona — Madrid — Valencia — Alicante — Seville — Malaga — Zaragoza — Bilbao — Vigo — A Coruna — Murcia — Palma de Mallorca — Las Palmas — Santa Cruz de Tenerife — Valladolid — Cordoba — Granada — Oviedo — Pamplona — Santander — Vitoria — Elche — Badalona — Cartagena — Jerez de la Frontera — Sabadell — Mostoles — Alcala de Henares — and all other localities in Spain.

The information is for educational purposes only and does not replace medical advice. Consult your doctor or urologist before starting any treatment for erectile dysfunction.