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Cialis Soft Tabs (Tadalafil 20mg)

Medically reviewed by Dr. Carlos Méndez Ruiz, Urologist, Registration No. 03-45678, Official College of Physicians of Alicante — Updated January 2026.

Cialis Soft Tabs contains exactly the same active ingredient as all other tadalafil formulations — the molecule itself does not change. What changes is the release technology: a soft chewable tablet that breaks down in the mouth combining buccal and gastric absorption, eliminating the need for water and adding a fruity or mint flavour. The practical result is an onset of action of 20 to 30 minutes — faster than a standard swallowed tablet (~2 hours), and in the same range as sublingual Cialis Professional, though through a different absorption mechanism. From €3.71 per pill with discreet delivery in 4-7 days across Spain.

Product Dosage Quantity + Bonus Price Order
Cialis Soft Tabs 20mg 10 pills 37.17
Cialis Soft Tabs 20mg 20 + 2 pills 63.79
Cialis Soft Tabs 20mg 30 + 4 pills 83.27
Cialis Soft Tabs 20mg 60 + 4 pills 151.78
Cialis Soft Tabs 20mg 90 + 6 pills 206.39
Cialis Soft Tabs 20mg 120 + 6 pills 236.80
Cialis Soft Tabs 20mg 180 + 8 pills 336.35
Cialis Soft Tabs 20mg 270 + 10 pills 448.95

How the Chewable Tablet Works — The Real Difference From Other Formulations

Understanding why a chewable tablet acts differently from a swallowed one requires a brief look at what happens during chewing. When a soft tablet is chewed:

  1. Contact surface multiplies ×10 — breaking the tablet into small particles dramatically increases the surface exposed to saliva and oral mucosa, accelerating dissolution of the active ingredient
  2. Direct buccal absorption — part of the tadalafil is absorbed directly through the mouth and gum mucosa before being swallowed, partially bypassing hepatic first-pass metabolism
  3. Faster gastric absorption — already-dissolved particles arrive at the stomach in a near-predissolved state, accelerating intestinal absorption

The net result is a shorter Tmax (time to maximum plasma concentration) compared to a coated tablet swallowed whole, where the capsule must first disintegrate, then the active ingredient dissolve, then be absorbed in the small intestine — a process that with standard tadalafil can take ~2 hours.

Tadalafil Formulation Comparison — Clinically Relevant Differences
Parameter Cialis Soft Tabs
Chewable
Cialis Professional
Sublingual
Generic tadalafil
Standard tablet
Active ingredient Tadalafil (same) Tadalafil (same) Tadalafil (same)
Administration technique Chew and swallow Dissolve under tongue Swallow whole with water
Onset of action 20–30 min 15–20 min ~2 hours
Water required No No Yes
Flavour Fruity / mint Neutral Neutral (coated)
Fatty meal effect No clinical effect No clinical effect No clinical effect
Duration of effect Up to 36 hours Up to 36 hours Up to 36 hours
Suitable for dysphagia Yes Yes No
Price from (cialiscomprar.com) €3.71/pill €4.59/pill €1.10/pill

Clinical note on xerostomia (dry mouth): In men over 60 taking anticholinergics, tricyclic antidepressants, or antihistamines — medications that frequently cause dry mouth — absorption of chewable tablets may be slightly reduced due to lower saliva production. In these cases, sublingual Cialis Professional may be more effective as it relies on direct mucosal dissolution rather than chewing.

How Tadalafil Works — The Mechanism

Regardless of the formulation, tadalafil always works through the same mechanism. Sexual stimulation triggers the release of nitric oxide (NO) at nerve terminals in the corpus cavernosum. NO activates guanylate cyclase, converting GTP to cyclic GMP (cGMP). Elevated cGMP relaxes smooth muscle in cavernosal arteries, increases blood flow and produces erection. PDE5 is the enzyme that normally degrades cGMP — tadalafil selectively blocks it, prolonging and amplifying the erectile response.

No sexual stimulation = no effect: Cialis Soft Tabs — like any PDE5 inhibitor — does not produce erections autonomously. Without sexual arousal there is no NO release, no cGMP, and no erectile effect. The medication amplifies the normal physiological response to stimulation; it does not replace it.

Cialis Soft Tabs chewable tadalafil dosage 20mg

Dosage — How to Take Cialis Soft Tabs Correctly

Administration technique — the detail most product sheets omit

  1. Chew the tablet slowly for 15-20 seconds — do not swallow it whole (swallowing whole removes the formulation advantage — it will act like a standard tablet with ~2 hour onset)
  2. Hold the chewed material in your mouth for a few additional seconds before swallowing — this maximises direct buccal absorption
  3. Do not drink water immediately afterwards — water dilutes the active ingredient still being absorbed through the oral mucosa
  4. Take 20-30 minutes before planned sexual activity

Dose

  • Standard dose: 20mg — 1 chewable tablet, maximum once per day
  • Adults over 65: start with 10mg; tadalafil exposure increases 40-52% in this age group due to reduced clearance
  • Severe renal impairment (CrCl <30 mL/min): do not exceed 10mg every 48 hours
  • Food: no clinically relevant interaction — take with or without meals

When to Choose Cialis Soft Tabs — and When Not To

Best choice: Cialis Soft Tabs if...

  • You have difficulty swallowing tablets (dysphagia, gag reflex, pill anxiety)
  • You prefer not to need water — useful in spontaneous situations away from home
  • The fruity or mint flavour makes taking the medication more pleasant
  • You want faster onset than standard (20-30 min vs 2h) without the cost of Cialis Professional
  • Mild dry mouth — chewing generates additional saliva that helps absorption

Consider other options if...

  • You need the fastest possible onset (15-20 min) — choose sublingual Cialis Professional
  • You have severe xerostomia — chewing will be less effective; choose sublingual
  • Price is the main factor — standard generic tadalafil (€1.10/pill) produces the same effect at lower cost if 2-hour planning is acceptable
  • You prefer continuous coverage — tadalafil 5mg daily eliminates any planning requirement
  • You prefer gel format — consider Apcalis SX Oral Jelly, tadalafil in liquid format

Contraindications and Warnings

ABSOLUTE CONTRAINDICATIONS

  • Nitrates in any form — nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, "poppers". Risk of potentially fatal severe hypotension. Mandatory window: 48 hours between tadalafil and nitrates (in both directions)
  • Riociguat (Adempas) — absolute contraindication with all PDE5 inhibitors
  • Hypersensitivity to tadalafil or any excipient
  • Severe hepatic impairment (Child-Pugh C)
  • Under 18 years of age

CAUTION — Consult your doctor

  • Antihypertensives — additive blood pressure-lowering effect
  • Alpha-blockers (tamsulosin, doxazosin) — postural hypotension risk
  • Strong CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin) — increase tadalafil levels; do not exceed 10mg/72h
  • Uncontrolled hypertension (BP >170/100) or hypotension (BP <90/50)
  • Recent ischaemic heart disease (MI in past 90 days)
  • Severe renal impairment (CrCl <30 mL/min)
  • Retinitis pigmentosa; previous priapism

Side Effects

Common (1–10% of users)

  • Headache — most common; mild and self-limiting
  • Dyspepsia — mild gastric discomfort
  • Facial flushing
  • Back pain and myalgia — tadalafil-specific; due to PDE11 inhibition in muscle tissue; appears 12-24h after the dose, resolves within 48h without treatment
  • Nasal congestion
  • Dizziness

Rare — seek immediate medical attention

  • Priapism (erection >4 hours) — urological emergency; go to A&E immediately
  • NAION — sudden vision loss; stop the medication immediately
  • Sudden hearing loss
  • Severe hypotension — especially if accidentally combined with nitrates

Cialis Soft Tabs chewable tadalafil price Spain delivery

Cialis Soft Tabs Prices — cialiscomprar.com

Quantity Total price Price per pill
10 pills €37.17 €3.72
20 + 2 free €63.79 €2.90
30 + 4 free €83.27 €2.45
90 + 6 free €206.39 €2.15 — best value
180 + 8 free €336.35 €1.78 — lowest price

All prices include discreet delivery across Spain in 4-7 business days, unmarked packaging, and a tracking number with every order.

Frequently Asked Questions — Cialis Soft Tabs

Should Cialis Soft Tabs be chewed or can they be swallowed whole? They must be chewed. Swallowing whole removes the formulation advantage — the tablet will act like a standard tablet with ~2 hour onset. To benefit from the faster onset (20-30 min), chew slowly for 15-20 seconds and hold in the mouth before swallowing.

How does it differ from Cialis Professional? Both are fast-acting tadalafil formulations that don't require water. The difference is in the mechanism: Cialis Professional is sublingual (dissolves under the tongue without chewing) with onset in 15-20 min; Cialis Soft Tabs is chewable with onset in 20-30 min. Soft Tabs has flavour; Professional is neutral. For the fastest onset: Professional. For a more pleasant flavoured experience with no clinically significant speed difference: Soft Tabs.

Does food affect Cialis Soft Tabs? No. Tadalafil has no clinically relevant interaction with food in any of its formulations — unlike sildenafil, which reduces absorption by 29% with fatty meals. You can take Cialis Soft Tabs before, during or after a meal without affecting efficacy.

How long does the effect last? Up to 36 hours after the dose. This means the enhanced erectile response to sexual stimulation is available throughout that window — not a continuous 36-hour erection. The erection appears with sexual stimulation and resolves normally when it concludes.

How long to wait between Cialis Soft Tabs and nitrates? 48 hours — double that of sildenafil or vardenafil (24 hours). This safety window applies in both directions: 48 hours after taking tadalafil before using nitrates, and avoid tadalafil within 48 hours of a long-acting nitrate.

Can I take Cialis Soft Tabs if I have dental prosthetics or implants? Yes. Chewing a soft tablet does not generate the pressure that would affect prosthetics or implants. If you have any doubt about your specific situation, consult your dentist.

Other Tadalafil Products at cialiscomprar.com

This page is informational and does not replace medical consultation. Tadalafil requires a prescription in Spain. Absolute contraindication with nitrates — mandatory 48-hour window. In case of erection lasting more than 4 hours, go to A&E immediately. Reviewed by Dr. Carlos Méndez Ruiz, Urologist, Registration No. 03-45678 — January 2026.